A new approach to landscape ecology involves the application of the eco-field hypothesis and the General Theory of Resources. In this study, we describe the putative eco-field of bark beetles as a spatial configuration with a specific meaning-carrier for every organism-resource interaction. Bark beetles are insects with key roles in matter and energy cycles in coniferous forests, which cause significant changes to forestry landscapes when outbreaks occur. Bark beetles are guided towards host trees by the recognition of semiotic signals using (...) a specific eco-field. These signals mainly comprise a group of scents, which are called the odourtope. Their interactions with other organisms occur by sharing relevant information from the eco-field networks in the forest ecosystem. The eco-field networks modulate the expansion of the realized semiotic niche of the bark beetle towards the potential semiotic niche. Moreover, the niche construction process can be initiated by interchanging signals among species living in the same place, where these signals allow the exploitation of the required resources. If different organisms are interdependent on signals in eco-field networks, then this process may result in the establishment of mutualistic relationships. This is an example of how evolutionary processes are initiated by the recognition of signals in a network of eco-fields. (shrink)

Pathological tremor is a common but highly complex movement disorder, affecting ~5% of population older than 65 years. Different methodologies have been proposed for its quantification. Nevertheless, the discrimination between Parkinson’s disease tremor and essential tremor remains a daunting clinical challenge, greatly impacting patient treatment and basic research. Here, we propose and compare several movement-based and electromyography-based tremor quantification metrics. For the latter, we identified individual motor unit discharge patterns from high-density surface electromyograms and characterized the neural drive to a (...) single muscle and how it relates to other affected muscles in 27 Parkinson’s disease and 27 essential tremor patients. We also computed several metrics from the literature. The most discriminative metrics were the symmetry of the neural drive to muscles, motor unit synchronization, and the mean log power of the tremor harmonics in movement recordings. Noteworthily, the first two most discriminative metrics were proposed in this study. We then used decision tree modelling to find the most discriminative combinations of individual metrics, which increased the accuracy of tremor type discrimination to 94%. In summary, the proposed neural drive-based metrics were the most accurate at discriminating and characterizing the two most common pathological tremor types. (shrink)

We consider the problem of mixing in the f 0(980)–a 0(980) system when width effects are taken into account. By explicit calculation we show that two mixing angles are necessary to describe the phenomenon.

Recent articles in Religious Studies have underscored the questions of whether Buddhism presents any empirical doctrines, and whether, if it does, such doctrines are false or vacuous. In what follows I want to sketch an interpretation of Buddhism according to which it does not offer doctrines which are empirically false, on the one hand, or trivially true on the other. In doing so I take my cue from an earlier, and by now classic, paper by H. H. Price. For the (...) exposition of Buddhism I take the Pali Nikāyas, the single most significant collection of texts in the Buddhist tradition. The particular doctrine which is the focus of discussion here is the kammavāda or ‘karma view’ of early Indian Buddhism, for it is the focus of much of the recent literature cited above and a doctrine which some have thought amenable to statement in empirical terms. (shrink)

Geannoteerde briefwisseling van de twee geleerden over het vraagstuk van de evolutie.

This appraisal of two of the most fundamental terms in the moral language of Thomas Aquinas draws on the contemporary moral distinction between the goodness of a person and the rightness of a person's living. Keenan thus finds that Aquinas's earlier writings do not permit the possibility of such a distinction. But in his mature works, specifically the Summa Theologiae, Thomas describes the human act of moral intentionality, and even the virtues in a way analogous to our use of the (...) term moral rightness. To Thomas, only the virtue of charity expresses moral goodness. And, although Thomas describes vices and sin as wrong conduct, he never really develops a description for moral badness.Keenan compels us to carefully examine Thomas's central moral concepts and to measure them against contemporary standards for meaning and correctness. As a result, any student of Thomas will find here a forceful argument that his notion of the good is considerably different from ours. Similarly, ethicists and moral theologians will find in the Thomas presented here a consistent-virtue ethicist concerned with descriptions for right living. Any student of theology will also find here a Thomas whose critical and concrete thinking enabled him to develop and even abandon earlier positions as his comprehension of the Good evolved. This analysis prompts a re-examination of our own concepts. Measuring Thomas's standards against our own, Keenan obliges us to ask whether we sufficiently understand rightness and moral intentionality. He also asks whether we correctly describe what it means to will or to desire something. He further questions whether we have surrendered our understanding of the virtues to the voluntarism and subjectivism which Thomas relentlessly critiqued. This historically sophisticated reading of the Summa Thologiae both allows Thomas to speak again as he once did, and affords us the chance to evaluate the way we describe ourselves and one another as being good and living rightly. (shrink)

Transplantation research on samples and organs from deceased donors in England, Wales and Northern Ireland is under threat. The key problems relate to difficulties encountered in gaining consent for research projects, as distinct from consent to donation for clinical transplantation. They are due partly to the terms of the Human Tissue Act 2004 (the 2004 Act), and partly to its interpretation by the Human Tissue Authority (HTA). They include excessive interaction with donor representatives regarding ‘informed consent’ to research projects, uncertainty (...) as to the scope and duration of a donor's ‘authority’ over an organ, and restrictions caused by the apparent need for licensing of transplantation research under the 2004 Act, combined with lack of certainty, or guidance, as to the distinction between ‘research’, which requires a licence, and ‘service development’, which does not. In our view this confusion hinders and deters Specialist Nurses for Organ Donation in approaching donor representatives and discussing possible research projects with them. It has also, as we have reported elsewhere, led to abandonment of research projects for fear of liability, despite both Research Ethics Committee (REC) approval and donor consent. Such problems do not seem to occur under the transplant laws of most other comparable jurisdictions. The Transplantation Ethics Symposium, ‘The ethics of organ retrieval: goals, rights and responsibilities’, hosted by the MRC Centre for Transplantation at King's College London in December 2010, revealed that many senior clinicians and researchers, administrators, and lawyers are both unclear and in disagreement concerning the effects of the 2004 Act and the extent to which it is adhered to or ignored in practice. In this paper we examine the difficulties encountered and suggest solutions based on a less restrictive interpretation of the 2004 Act, or, more probably, a regulatory change under its authority. We propose that, in the long term, a law which includes consent for REC-approved research within the general consent for organ donation and transplantation seems preferable to the present system, both ethically and in practical terms. (shrink)

John Locke:When we set before our eyes a round globe of uniform colour, v.g. gold, alabaster or jet, it is certain that the idea thereby imprinted in our mind is of a flat circle, variously shadowed, with several degrees of light and brightness coming to our eyes. But we having, by use, been accustomed to perceive what kind of appearance convex bodies are wont to make in us, what alterations are made in the reflections of light by the difference of (...) the sensible figures of bodies: the judgment presently, by an habitual custom, alters the appearances into their causes.H.H. Price:…. a distant hillside which is full of protuberances, and slopes upwards at quite a gentle angle, will appear flat and vertical….. This means that the sense-datum, the colour expanse which we sense, actually is flat and vertical. (shrink)

But beyond doubt also, the primacy that Plato gives to the imitation of, or participation in the Ideas, apparently substantially existing, is the main reason why critics have refused to recognize or consider possible any mode of conceptual immanence in the mind of the Demiurge or whomever they regard as the Platonic God. Text on text could be cited to exemplify the role of the Ideas as archetypes. Yet it seems rather strange that Plato should conceive of two simultaneous objects (...) of imitation, the Supreme Being and the Ideas. Despite the plurality of Ideas, however, some critics have recognized a centripetal tendency in the dialogues toward the primacy of the Good, or the One, or the Beautiful, or Being, over subordinate Ideas. Was there possibly some similar tendency toward unity of some sort between the Supreme Intellect and the Intelligibles, his archetypes, which in the Timaeus are the ideal Living Exemplar of the cosmos? (shrink)

Context. The identification of the sources that reionized the Universe and their specific contribution to this process are key missing pieces of our knowledge of the early Universe. Faint star-forming galaxies may be the main contributors to the ionizing photon budget during the epoch of reionization, but their escaping photons cannot be detected directly due to inter-galactic medium opacity. Hence, it is essential to characterize the properties of faint galaxies with significant Lyman continuum photon leakage up to z 4 to (...) define indirect indicators allowing analogues to be found at the highest redshift. Aims. Long gamma-ray bursts explode typically in star-forming regions of faint, star-forming galaxies. Through LGRB afterglow spectroscopy it is possible to detect directly LyC photons. Our aim is to use LGRBs as tools to study LyC leakage from faint, star-forming galaxies at high redshift. Methods. Here we present the observations of LyC emission in the afterglow spectra of GRB 191004B at z = 3:5055, together with those of the other two previously known LyC-emitting LGRB, to determine their LyC escape fraction and compare their properties. Results. From the afterglow spectrum of GRB 191004B we determine a neutral hydrogen column density at the LGRB redshift of og =17:2 0:15, and negligible extinction. The only metal absorption lines detected are C iv and Si iv. In contrast to GRB 050908 and GRB 060607A, the host galaxy of GRB 191004B displays significant Ly emission. From its Ly emission and the non-detection of Balmer emission lines we constrain its star-formation rate to 1 SFR 4:7 M yr. 1. We fit the Ly emission with a shell model and find parameters values consistent with the observed ones. The absolute LyC escape fractions we find for GRB 191004B, GRB 050908 and GRB 060607A are of 0:35+0:10.0:11, 0:08+0:05.0:04 and :20+0:05.0:05, respectively. We compare the LyC escape fraction of LGRBs to the values of other LyC emitters found from the literature, showing that LGRB afterglows can be powerful tools to study LyC escape for faint high-redshift star-forming galaxies. Indeed we could push LyC leakage studies to much higher absolute magnitudes. The host galaxies of the three LGRB presented here have all M1600 >.19:5 mag, with the GRB 060607A host at M1600 >.16 mag. LGRB hosts may therefore be particularly suitable for exploring the ionizing escape fraction in galaxies that are too faint or distant for conventional techniques. Furthermore the time investment is very small compared to galaxy studies. (shrink)